Reaction Details | |||
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Target | Neuropeptide Y receptor type 5 | ||
Ligand | BDBM50380915 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_813976 (CHEMBL2020488) | ||
Ki | 0.8±n/a nM | ||
Citation | Fichtner, M; Lee, E; Tomlinson, E; Scott, D; Cornelius, P; Patterson, TA; Carpino, PA Discovery and evaluation of spirocyclic derivatives as antagonists of the neuropeptide Y5 receptor. Bioorg Med Chem Lett22:2738-43 (2012) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Neuropeptide Y receptor type 5 | |||
Name: | Neuropeptide Y receptor type 5 | ||
Synonyms: | NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor | ||
Type: | Enzyme | ||
Mol. Mass.: | 50746.64 | ||
Organism: | Homo sapiens (Human) | ||
Description: | Q15761 | ||
Residue: | 445 | ||
Sequence: |
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BDBM50380915 | |||
n/a | |||
Name | BDBM50380915 | ||
Synonyms: | CHEMBL2016682 | ||
Type | Small organic molecule | ||
Emp. Form. | C23H22FN5O3 | ||
Mol. Mass. | 435.4509 | ||
SMILES | CN([C@H]1CC[C@]2(CC1)OC(=O)c1ccncc21)C(=O)Nc1ccn(n1)-c1ccccc1F |r,wU:2.1,5.8,(-.8,-22.44,;-.84,-23.98,;-2.2,-24.72,;-2.2,-26.26,;-3.53,-27.02,;-4.86,-26.25,;-4.87,-24.71,;-3.53,-23.95,;-4.7,-27.78,;-6.11,-28.41,;-6.44,-29.92,;-7.14,-27.26,;-8.67,-27.26,;-9.44,-25.93,;-8.68,-24.6,;-7.14,-24.6,;-6.37,-25.93,;.47,-24.79,;.54,-26.33,;1.8,-24,;3.09,-24.85,;4.54,-24.3,;5.51,-25.51,;4.66,-26.8,;3.17,-26.39,;5.41,-28.14,;4.62,-29.46,;5.37,-30.81,;6.92,-30.83,;7.71,-29.5,;6.95,-28.16,;7.74,-26.83,)| | ||
Structure |