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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Neuropeptide Y receptor type 5 | ||
| Ligand | BDBM50380919 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_813976 (CHEMBL2020488) | ||
| Ki | 8±n/a nM | ||
| Citation |  Fichtner, M; Lee, E; Tomlinson, E; Scott, D; Cornelius, P; Patterson, TA; Carpino, PA Discovery and evaluation of spirocyclic derivatives as antagonists of the neuropeptide Y5 receptor. Bioorg Med Chem Lett22:2738-43 (2012) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Neuropeptide Y receptor type 5 | |||
| Name: | Neuropeptide Y receptor type 5 | ||
| Synonyms: | NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 50746.64 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q15761 | ||
| Residue: | 445 | ||
| Sequence: |
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| BDBM50380919 | |||
| n/a | |||
| Name | BDBM50380919 | ||
| Synonyms: | CHEMBL2016736 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C24H25FN4O2 | ||
| Mol. Mass. | 420.4793 | ||
| SMILES | CN([C@H]1CC[C@@]2(COc3ccccc23)CC1)C(=O)Nc1ccn(n1)-c1ccccc1F |r,wU:2.1,5.5,(26.05,3.87,;26.01,2.33,;24.66,1.59,;24.65,.06,;23.33,-.71,;21.99,.06,;22.15,-1.47,;20.74,-2.1,;19.72,-.95,;18.18,-.95,;17.41,.38,;18.18,1.71,;19.72,1.72,;20.49,.38,;21.99,1.6,;23.33,2.37,;27.33,1.53,;27.4,-.02,;28.66,2.31,;29.95,1.46,;31.4,2.01,;32.36,.81,;31.52,-.48,;30.03,-.08,;32.27,-1.83,;31.48,-3.15,;32.23,-4.5,;33.77,-4.52,;34.56,-3.19,;33.81,-1.85,;34.59,-.52,)| | ||
| Structure | 
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