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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Neuropeptide Y receptor type 5 | ||
| Ligand | BDBM50380921 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_813976 (CHEMBL2020488) | ||
| Ki | 188±n/a nM | ||
| Citation |  Fichtner, M; Lee, E; Tomlinson, E; Scott, D; Cornelius, P; Patterson, TA; Carpino, PA Discovery and evaluation of spirocyclic derivatives as antagonists of the neuropeptide Y5 receptor. Bioorg Med Chem Lett22:2738-43 (2012) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Neuropeptide Y receptor type 5 | |||
| Name: | Neuropeptide Y receptor type 5 | ||
| Synonyms: | NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 50746.64 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q15761 | ||
| Residue: | 445 | ||
| Sequence: |
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| BDBM50380921 | |||
| n/a | |||
| Name | BDBM50380921 | ||
| Synonyms: | CHEMBL2016738 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C24H24FN5O3 | ||
| Mol. Mass. | 449.4775 | ||
| SMILES | CN([C@H]1CC[C@@]2(CC1)Cc1cnccc1C(=O)O2)C(=O)Nc1ccn(n1)-c1ccccc1F |r,wU:2.1,5.19,(24.41,-6.79,;24.37,-8.33,;23.01,-9.07,;23.01,-10.61,;21.68,-11.37,;20.35,-10.6,;20.34,-9.07,;21.68,-8.3,;19.01,-9.83,;17.69,-10.6,;16.36,-9.83,;15.02,-10.59,;15.02,-12.14,;16.35,-12.9,;17.68,-12.14,;19.02,-12.91,;19.02,-14.45,;20.36,-12.14,;25.68,-9.14,;25.75,-10.68,;27.01,-8.36,;28.29,-9.2,;29.74,-8.65,;30.7,-9.86,;29.86,-11.14,;28.37,-10.74,;30.61,-12.49,;29.82,-13.81,;30.57,-15.15,;32.11,-15.18,;32.9,-13.84,;32.15,-12.51,;32.93,-11.18,)| | ||
| Structure | 
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