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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Neuropeptide Y receptor type 5 | ||
| Ligand | BDBM50380924 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_813976 (CHEMBL2020488) | ||
| Ki | 82±n/a nM | ||
| Citation |  Fichtner, M; Lee, E; Tomlinson, E; Scott, D; Cornelius, P; Patterson, TA; Carpino, PA Discovery and evaluation of spirocyclic derivatives as antagonists of the neuropeptide Y5 receptor. Bioorg Med Chem Lett22:2738-43 (2012) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Neuropeptide Y receptor type 5 | |||
| Name: | Neuropeptide Y receptor type 5 | ||
| Synonyms: | NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 50746.64 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q15761 | ||
| Residue: | 445 | ||
| Sequence: |
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| BDBM50380924 | |||
| n/a | |||
| Name | BDBM50380924 | ||
| Synonyms: | CHEMBL2016741 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C25H25N5O3 | ||
| Mol. Mass. | 443.4977 | ||
| SMILES | CN([C@H]1CC[C@@]2(CC1)Cc1cnccc1C(=O)O2)C(=O)Nc1cnc(cn1)-c1ccccc1 |r,wU:2.1,5.19,(2.44,4.28,;2.4,2.73,;1.04,2,;1.04,.46,;-.29,-.3,;-1.62,.47,;-1.63,2,;-.29,2.77,;-2.96,1.24,;-4.28,.47,;-5.61,1.24,;-6.95,.48,;-6.95,-1.07,;-5.62,-1.84,;-4.29,-1.08,;-2.95,-1.85,;-2.95,-3.39,;-1.61,-1.07,;3.71,1.93,;3.78,.39,;5.04,2.71,;6.38,1.95,;7.71,2.72,;9.05,1.96,;9.05,.41,;7.71,-.36,;6.38,.41,;10.39,-.36,;10.39,-1.9,;11.72,-2.67,;13.06,-1.9,;13.05,-.35,;11.71,.41,)| | ||
| Structure | 
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