| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50381032 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_814123 (CHEMBL2020717) |
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| Ki | 80.8±n/a nM |
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| Citation |  Nagase, H; Akiyama, J; Nakajima, R; Hirayama, S; Nemoto, T; Gouda, H; Hirono, S; Fujii, H Synthesis of new opioid derivatives with a propellane skeleton and their pharmacology. Part 2: Propellane derivatives with an amide side chain. Bioorg Med Chem Lett22:2775-9 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOR-1 | Mor | OPIATE Mu | OPRM_MOUSE | Opioid receptors; mu and delta | Oprm | Oprm1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44431.62 |
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| Organism: | MOUSE |
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| Description: | OPIATE Mu OPRM1 MOUSE::P42866 |
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| Residue: | 398 |
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| Sequence: | MDSSAGPGNISDCSDPLAPASCSPAPGSWLNLSHVDGNQSDPCGPNRTGLGGSHSLCPQT
GSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST
LPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRT
PRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFA
FIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYV
IIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQ
QNSARIRQNTREHPSTANTVDRTNHQLENLEAETAPLP
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| BDBM50381032 |
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| n/a |
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| Name | BDBM50381032 |
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| Synonyms: | CHEMBL2017148 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H32N2O2 |
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| Mol. Mass. | 416.5552 |
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| SMILES | Oc1ccc2CC34C[C@H](CCC3(CCN(CC3CC3)C4)c2c1)C(=O)Nc1ccccc1 |r| |
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| Structure | 
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