| Reaction Details |
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 | Report a problem with these data |
| Target | B1 bradykinin receptor |
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| Ligand | BDBM50381265 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_814368 (CHEMBL2019577) |
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| Ki | 1.7±n/a nM |
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| Citation |  Eles, J; Beke, G; Vágó, I; Bozó, E; Huszár, J; Tarcsay, A; Kolok, S; Schmidt, E; Vastag, M; Hornok, K; Farkas, S; Domány, G; Keseru, GM Quinolinyl- and phenantridinyl-acetamides as bradykinin B1 receptor antagonists. Bioorg Med Chem Lett22:3095-9 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| B1 bradykinin receptor |
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| Name: | B1 bradykinin receptor |
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| Synonyms: | B1 BRADYKININ | B1 bradykinin receptor | B1R | BDKRB1 | BK-1 receptor | BKRB1_HUMAN | BRADYB1 | Bradykinin B1 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 40508.87 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P46663 |
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| Residue: | 353 |
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| Sequence: | MASSWPPLELQSSNQSQLFPQNATACDNAPEAWDLLHRVLPTFIISICFFGLLGNLFVLL
VFLLPRRQLNVAEIYLANLAASDLVFVLGLPFWAENIWNQFNWPFGALLCRVINGVIKAN
LFISIFLVVAISQDRYRVLVHPMASRRQQRRRQARVTCVLIWVVGGLLSIPTFLLRSIQA
VPDLNITACILLLPHEAWHFARIVELNILGFLLPLAAIVFFNYHILASLRTREEVSRTRC
GGRKDSKTTALILTLVVAFLVCWAPYHFFAFLEFLFQVQAVRGCFWEDFIDLGLQLANFF
AFTNSSLNPVIYVFVGRLFRTKVWELYKQCTPKSLAPISSSHRKEIFQLFWRN
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| BDBM50381265 |
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| n/a |
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| Name | BDBM50381265 |
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| Synonyms: | CHEMBL2018873 |
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| Type | Small organic molecule |
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| Emp. Form. | C33H30Cl2N4O4S |
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| Mol. Mass. | 649.587 |
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| SMILES | COc1cccc2C(CC(=O)NCCc3ccc(cc3)C3=NCCN3)N(c3ccccc3-c12)S(=O)(=O)c1ccc(Cl)c(Cl)c1 |t:21| |
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| Structure | 
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