Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetB1 bradykinin receptor
LigandBDBM50381275
Substrate/Competitorn/a
Meas. Tech.ChEMBL_814368 (CHEMBL2019577)
Ki 3.8±n/a nM
Citation Eles, JBeke, GVágó, IBozó, EHuszár, JTarcsay, AKolok, SSchmidt, EVastag, MHornok, KFarkas, SDomány, GKeseru, GM Quinolinyl- and phenantridinyl-acetamides as bradykinin B1 receptor antagonists. Bioorg Med Chem Lett22:3095-9 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
B1 bradykinin receptor
Name:B1 bradykinin receptor
Synonyms:B1 BRADYKININ | B1 bradykinin receptor | B1R | BDKRB1 | BK-1 receptor | BKRB1_HUMAN | BRADYB1 | Bradykinin B1 receptor
Type:Enzyme
Mol. Mass.:40508.87
Organism:Homo sapiens (Human)
Description:P46663
Residue:353
Sequence:
MASSWPPLELQSSNQSQLFPQNATACDNAPEAWDLLHRVLPTFIISICFFGLLGNLFVLL
VFLLPRRQLNVAEIYLANLAASDLVFVLGLPFWAENIWNQFNWPFGALLCRVINGVIKAN
LFISIFLVVAISQDRYRVLVHPMASRRQQRRRQARVTCVLIWVVGGLLSIPTFLLRSIQA
VPDLNITACILLLPHEAWHFARIVELNILGFLLPLAAIVFFNYHILASLRTREEVSRTRC
GGRKDSKTTALILTLVVAFLVCWAPYHFFAFLEFLFQVQAVRGCFWEDFIDLGLQLANFF
AFTNSSLNPVIYVFVGRLFRTKVWELYKQCTPKSLAPISSSHRKEIFQLFWRN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50381275
n/a
NameBDBM50381275
Synonyms:CHEMBL2018865
TypeSmall organic molecule
Emp. Form.C32H34Cl2N4O3S
Mol. Mass.625.608
SMILESClc1ccc(cc1Cl)S(=O)(=O)N1CCc2ccccc2C1CC(=O)N1CCC(Cc2ccc(cc2)C2=NCCN2)CC1 |t:39|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: