| Reaction Details |
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 | Report a problem with these data |
| Target | Acrosin |
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| Ligand | BDBM50382100 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_815401 (CHEMBL2027053) |
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| IC50 | 10700000±n/a nM |
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| Citation |  Liu, X; Chen, Q; Zhu, J; Fan, Y; Ding, L; Zhao, J; Han, G; Tian, W; Qi, J; Zhou, Y; Lv, J Synthesis and acrosin inhibitory activity of methyl 5-substituted-1H-benzo[d]imidazol-2-yl carbamate derivatives. Bioorg Med Chem Lett22:3554-9 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Acrosin |
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| Name: | Acrosin |
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| Synonyms: | ACR | ACRO_HUMAN | ACRS |
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| Type: | PROTEIN |
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| Mol. Mass.: | 45865.48 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1365286 |
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| Residue: | 421 |
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| Sequence: | MVEMLPTAILLVLAVSVVAKDNATCDGPCGLRFRQNPQGGVRIVGGKAAQHGAWPWMVSL
QIFTYNSHRYHTCGGSLLNSRWVLTAAHCFVGKNNVHDWRLVFGAKEITYGNNKPVKAPL
QERYVEKIIIHEKYNSATEGNDIALVEITPPISCGRFIGPGCLPHFKAGLPRGSQSCWVA
GWGYIEEKAPRPSSILMEARVDLIDLDLCNSTQWYNGRVQPTNVCAGYPVGKIDTCQGDS
GGPLMCKDSKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNALRMIQSA
TPPPPTTRPPPIRPPFSHPISAHLPWYFQPPPRPLPPRPPAAQPRPPPSPPPPPPPPASP
LPPPPPPPPPTPSSTTKLPQGLSFAKRLQQLIEVLKGKTYSDGKNHYDMETTELPELTST
S
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| BDBM50382100 |
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| n/a |
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| Name | BDBM50382100 |
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| Synonyms: | CHEMBL2023307 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H15F3N4O4S |
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| Mol. Mass. | 428.386 |
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| SMILES | COC(=O)Nc1nc2ccc(cc2[nH]1)S(=O)(=O)NCc1ccc(cc1)C(F)(F)F |
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| Structure | 
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