BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetRegulator of G-protein signaling 8
LigandBDBM50384776
Substrate/Competitorn/a
Meas. Tech.ChEMBL_821036
IC50 7600±n/a nM
Citation Turner EMBlazer LLNeubig RRHusbands SM Small Molecule Inhibitors of Regulator of G Protein Signalling (RGS) Proteins. ACS Med Chem Lett 3:146-150 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Regulator of G-protein signaling 8
Name:Regulator of G-protein signaling 8
Synonyms:Regulator of G-protein signaling 8 (RGS8)
Type:Enzyme Catalytic Domain
Mol. Mass.:20925.80
Organism:Homo sapiens (Human)
Description:gi_74355113
Residue:180
Sequence:
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVL
LSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPRE
VNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50384776
n/a
NameBDBM50384776
Synonyms:CHEMBL2037228
TypeSmall organic molecule
Emp. Form.C15H10ClFN2O2S
Mol. Mass.336.769
SMILESFc1ccc(Cn2c(=O)sn(-c3ccc(Cl)cc3)c2=O)cc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: