| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP2 subtype |
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| Ligand | BDBM50385133 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_822930 (CHEMBL2038101) |
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| EC50 | 2700±n/a nM |
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| Citation |  Kambe, T; Maruyama, T; Nakai, Y; Oida, H; Maruyama, T; Abe, N; Nishiura, A; Nakai, H; Toda, M Synthesis and evaluation of¿-lactam analogs of PGE2 as EP4 and EP2/EP4 agonists. Bioorg Med Chem20:3502-22 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin E2 receptor EP2 subtype |
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| Name: | Prostaglandin E2 receptor EP2 subtype |
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| Synonyms: | PE2R2_RAT | Prostanoid EP2 receptor | Ptger2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 39786.37 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1501400 |
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| Residue: | 357 |
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| Sequence: | MDNSFNDSRRVENCESRQYLLSDESPAISSVMFTAGVLGNLIALALLARRWRGDTGCSAG
SRTSISLFHVLVTELVLTDLLGTCLISPVVLASYSRNQTLVALAPESRACTYFAFTMTFF
SLATMLMLFAMALERYLAIGHPYFYRRRVSRRGGLAVLPAIYGVSLLFCSLPLLNYGEYV
QYCPGTWCFIQHGRTAYLQLYATVLLLLIVAVLGCNISVILNLIRMQLRSKRSRCGLSGS
SLRGPGSRRRGERTSMAEETDHLILLAIMTITFAVCSLPFTIFAYMDETSSRKEKWDLRA
LRFLSVNSIIDPWVFVILRPPVLRLMRSVLCCRTSLRAPEAPGASCSTQQTDLCGQL
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| BDBM50385133 |
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| n/a |
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| Name | BDBM50385133 |
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| Synonyms: | CHEMBL2036324 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H25N3O4S3 |
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| Mol. Mass. | 551.7 |
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| SMILES | O[C@@H](Cc1cccc(c1)-c1nc2ccccc2s1)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r| |
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| Structure | 
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