| Reaction Details |
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 | Report a problem with these data |
| Target | Peroxisome proliferator-activated receptor delta |
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| Ligand | BDBM50126021 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_822293 (CHEMBL2038596) |
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| IC50 | 20±n/a nM |
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| Citation |  Méndez-Lucio, O; Pérez-Villanueva, J; Castillo, R; Medina-Franco, JL Activity landscape modeling of PPAR ligands with dual-activity difference maps. Bioorg Med Chem20:3523-32 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peroxisome proliferator-activated receptor delta |
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| Name: | Peroxisome proliferator-activated receptor delta |
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| Synonyms: | NR1C2 | NUC1 | NUCI | Nuclear hormone receptor 1 | Nuclear receptor subfamily 1 group C member 2 | PPAR delta | PPAR-beta | PPARB | PPARD | PPARD_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor beta | Peroxisome proliferator-activated receptor delta |
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| Type: | Enzyme |
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| Mol. Mass.: | 49910.45 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q03181 |
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| Residue: | 441 |
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| Sequence: | MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQM
GCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKK
NRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSK
HIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKE
ISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNK
DGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGD
RPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRI
KKTETETSLHPLLQEIYKDMY
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| BDBM50126021 |
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| n/a |
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| Name | BDBM50126021 |
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| Synonyms: | CHEMBL23881 | {4-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-propylsulfanyl]-3-chloro-phenyl}-acetic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C22H25ClO5S |
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| Mol. Mass. | 436.949 |
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| SMILES | CCCc1c(O)c(ccc1OCCCSc1ccc(CC(O)=O)cc1Cl)C(C)=O |
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| Structure | 
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