| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin L2 |
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| Ligand | BDBM50385990 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_825258 (CHEMBL2043890) |
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| IC50 | 1500±n/a nM |
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| Citation |  Marques, EF; Bueno, MA; Duarte, PD; Silva, LR; Martinelli, AM; dos Santos, CY; Severino, RP; Brömme, D; Vieira, PC; Corrêa, AG Evaluation of synthetic acridones and 4-quinolinones as potent inhibitors of cathepsins L and V. Eur J Med Chem54:10-21 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cathepsin L2 |
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| Name: | Cathepsin L2 |
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| Synonyms: | CATL2 | CATL2_HUMAN | CTSL2 | CTSU | CTSV | Cathepsin U | Cathepsin V |
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| Type: | Enzyme |
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| Mol. Mass.: | 37341.06 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O60911 |
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| Residue: | 334 |
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| Sequence: | MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIE
LHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDW
RKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG
GFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAV
ATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVK
NSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV
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| BDBM50385990 |
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| n/a |
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| Name | BDBM50385990 |
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| Synonyms: | CHEMBL2042452 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H16N2O5 |
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| Mol. Mass. | 364.3514 |
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| SMILES | OC(=O)c1cc(ccc1Nc1cccc(OCc2ccccc2)c1)[N+]([O-])=O |
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| Structure | 
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