| Reaction Details |
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 | Report a problem with these data |
| Target | Toll-like receptor 2 |
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| Ligand | BDBM50358550 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_826175 (CHEMBL2049616) |
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| EC50 | 3.63±n/a nM |
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| Citation |  Salunke, DB; Shukla, NM; Yoo, E; Crall, BM; Balakrishna, R; Malladi, SS; David, SA Structure-activity relationships in human Toll-like receptor 2-specific monoacyl lipopeptides. J Med Chem55:3353-63 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Toll-like receptor 2 |
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| Name: | Toll-like receptor 2 |
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| Synonyms: | TIL4 | TLR2 | TLR2_HUMAN | Toll-like receptor 2 | Toll-like receptor 2 (TLR2) |
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| Type: | Protein |
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| Mol. Mass.: | 89837.58 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O60603 |
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| Residue: | 784 |
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| Sequence: | MPHTLWMVWVLGVIISLSKEESSNQASLSCDRNGICKGSSGSLNSIPSGLTEAVKSLDLS
NNRITYISNSDLQRCVNLQALVLTSNGINTIEEDSFSSLGSLEHLDLSYNYLSNLSSSWF
KPLSSLTFLNLLGNPYKTLGETSLFSHLTKLQILRVGNMDTFTKIQRKDFAGLTFLEELE
IDASDLQSYEPKSLKSIQNVSHLILHMKQHILLLEIFVDVTSSVECLELRDTDLDTFHFS
ELSTGETNSLIKKFTFRNVKITDESLFQVMKLLNQISGLLELEFDDCTLNGVGNFRASDN
DRVIDPGKVETLTIRRLHIPRFYLFYDLSTLYSLTERVKRITVENSKVFLVPCLLSQHLK
SLEYLDLSENLMVEEYLKNSACEDAWPSLQTLILRQNHLASLEKTGETLLTLKNLTNIDI
SKNSFHSMPETCQWPEKMKYLNLSSTRIHSVTGCIPKTLEILDVSNNNLNLFSLNLPQLK
ELYISRNKLMTLPDASLLPMLLVLKISRNAITTFSKEQLDSFHTLKTLEAGGNNFICSCE
FLSFTQEQQALAKVLIDWPANYLCDSPSHVRGQQVQDVRLSVSECHRTALVSGMCCALFL
LILLTGVLCHRFHGLWYMKMMWAWLQAKRKPRKAPSRNICYDAFVSYSERDAYWVENLMV
QELENFNPPFKLCLHKRDFIPGKWIIDNIIDSIEKSHKTVFVLSENFVKSEWCKYELDFS
HFRLFDENNDAAILILLEPIEKKAIPQRFCKLRKIMNTKTYLEWPMDEAQREGFWVNLRA
AIKS
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| BDBM50358550 |
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| n/a |
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| Name | BDBM50358550 |
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| Synonyms: | CHEMBL1923549 | US9676818, 6d |
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| Type | Small organic molecule |
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| Emp. Form. | C25H48N2O6S |
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| Mol. Mass. | 504.723 |
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| SMILES | CCCCCCCCCCCCCCCC(=O)OCCSC[C@H](N)C(=O)N[C@@H](CO)C(=O)OC |r| |
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| Structure | 
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