| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Mu-type opioid receptor |
|---|
| Ligand | BDBM50387553 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_830314 (CHEMBL2060903) |
|---|
| Ki | 83.2±n/a nM |
|---|
| Citation |  Nagase, H; Imaide, S; Hirayama, S; Nemoto, T; Fujii, H Essential structure of opioid¿ receptor agonist nalfurafine for binding to the¿ receptor 2: synthesis of decahydro(iminoethano)phenanthrene derivatives and their pharmacologies. Bioorg Med Chem Lett22:5071-4 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Mu-type opioid receptor |
|---|
| Name: | Mu-type opioid receptor |
|---|
| Synonyms: | M-OR-1 | MOR-1 | Mor | OPIATE Mu | OPRM_MOUSE | Opioid receptors; mu and delta | Oprm | Oprm1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 44431.62 |
|---|
| Organism: | MOUSE |
|---|
| Description: | OPIATE Mu OPRM1 MOUSE::P42866 |
|---|
| Residue: | 398 |
|---|
| Sequence: | MDSSAGPGNISDCSDPLAPASCSPAPGSWLNLSHVDGNQSDPCGPNRTGLGGSHSLCPQT
GSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST
LPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRT
PRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFA
FIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYV
IIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQ
QNSARIRQNTREHPSTANTVDRTNHQLENLEAETAPLP
|
|
|
|---|
| BDBM50387553 |
|---|
| n/a |
|---|
| Name | BDBM50387553 |
|---|
| Synonyms: | CHEMBL2057691 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C28H38N2O3 |
|---|
| Mol. Mass. | 450.6129 |
|---|
| SMILES | CN([C@@H]1CC[C@@]2(O)[C@H]3CC4=C(CCCC4)[C@@]2(CCN3CC2CC2)C1)C(=O)\C=C\c1ccoc1 |r,t:9| |
|---|
| Structure | 
|
|---|
Search and Browse
