| Reaction Details |
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 | Report a problem with these data |
| Target | M-phase inducer phosphatase 3 |
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| Ligand | BDBM26613 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_829766 (CHEMBL2061285) |
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| IC50 | >10000±n/a nM |
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| Citation |  Mak, LH; Knott, J; Scott, KA; Scott, C; Whyte, GF; Ye, Y; Mann, DJ; Ces, O; Stivers, J; Woscholski, R Arylstibonic acids are potent and isoform-selective inhibitors of Cdc25a and Cdc25b phosphatases. Bioorg Med Chem20:4371-6 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| M-phase inducer phosphatase 3 |
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| Name: | M-phase inducer phosphatase 3 |
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| Synonyms: | CDC25C | Dual specificity phosphatase Cdc25C | M-phase inducer phosphatase 3 | MPIP3_HUMAN |
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| Type: | Substrate |
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| Mol. Mass.: | 53366.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30307 |
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| Residue: | 473 |
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| Sequence: | MSTELFSSTREEGSSGSGPSFRSNQRKMLNLLLERDTSFTVCPDVPRTPVGKFLGDSANL
SILSGGTPKRCLDLSNLSSGEITATQLTTSADLDETGHLDSSGLQEVHLAGMNHDQHLMK
CSPAQLLCSTPNGLDRGHRKRDAMCSSSANKENDNGNLVDSEMKYLGSPITTVPKLDKNP
NLGEDQAEEISDELMEFSLKDQEAKVSRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDK
VKKKYFSGQGKLRKGLCLKKTVSLCDITITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQ
DLKYVNPETVAALLSGKFQGLIEKFYVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKK
PIVPLDTQKRIIIVFHCEFSSERGPRMCRCLREEDRSLNQYPALYYPELYILKGGYRDFF
PEYMELCEPQSYCPMHHQDHKTELLRCRSQSKVQEGERQLREQIALLVKDMSP
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| BDBM26613 |
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| n/a |
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| Name | BDBM26613 |
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| Synonyms: | (2E)-3-{3-[dihydroxy(oxo)--stibanyl]phenyl}prop-2-enoic acid | Compound 13778 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H9O5Sb |
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| Mol. Mass. | 318.92 |
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| SMILES | OC(=O)\C=C\c1cccc(c1)[Sb](O)(O)=O |
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| Structure | 
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