| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50389025 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_833110 (CHEMBL2067353) |
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| Ki | 2.1±n/a nM |
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| Citation |  Oberdorf, C; Schepmann, D; Vela, JM; Buschmann, H; Holenz, J; Wünsch, B Thiophene bioisosteres of spirocyclics receptor ligands: relationships between substitution pattern ands receptor affinity. J Med Chem55:5350-60 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25124.85 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q99720 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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| BDBM50389025 |
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| n/a |
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| Name | BDBM50389025 |
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| Synonyms: | CHEMBL2064198 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H21NOS |
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| Mol. Mass. | 299.43 |
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| SMILES | C(N1CCC2(CC1)OCCc1sccc21)c1ccccc1 |
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| Structure | 
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