| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50389562 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_832746 (CHEMBL2067842) |
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| Ki | >450±n/a nM |
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| Citation |  Hayashi, S; Ohashi, K; Nakata, E; Emoto, C Discovery of 1-(ß-amino substituted-ß-alanyl)-N,N-dimethylindoline-2-carboxamides as novel nonpeptide antagonists of nociceptin/orphanin FQ receptor: efficient design, synthesis, and structure-activity relationship studies. Eur J Med Chem55:228-42 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44789.51 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35372 |
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| Residue: | 400 |
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| Sequence: | MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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| BDBM50389562 |
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| n/a |
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| Name | BDBM50389562 |
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| Synonyms: | CHEMBL2064135 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H34N4O2 |
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| Mol. Mass. | 434.5738 |
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| SMILES | CC(N1CCN(CCC(=O)N2C(Cc3ccccc23)C(=O)N(C)C)CC1)c1ccccc1 |
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| Structure | 
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