| Reaction Details |
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 | Report a problem with these data |
| Target | Cytochrome P450 2J2 |
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| Ligand | BDBM50319983 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_834085 (CHEMBL2072825) |
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| IC50 | >10000±n/a nM |
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| Citation |  Shen, HC; Hammock, BD Discovery of inhibitors of soluble epoxide hydrolase: a target with multiple potential therapeutic indications. J Med Chem55:1789-808 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytochrome P450 2J2 |
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| Name: | Cytochrome P450 2J2 |
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| Synonyms: | CP2J2_HUMAN | CYP2J2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 57623.04 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P51589 |
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| Residue: | 502 |
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| Sequence: | MLAAMGSLAAALWAVVHPRTLLLGTVAFLLAADFLKRRRPKNYPPGPWRLPFLGNFFLVD
FEQSHLEVQLFVKKYGNLFSLELGDISAVLITGLPLIKEALIHMDQNFGNRPVTPMREHI
FKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEERIQEEAQHLTEAIKEENGQPFDP
HFKINNAVSNIICSITFGERFEYQDSWFQQLLKLLDEVTYLEASKTCQLYNVFPWIMKFL
PGPHQTLFSNWKKLKLFVSHMIDKHRKDWNPAETRDFIDAYLKEMSKHTGNPTSSFHEEN
LICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAARESMP
YTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDT
FNPDHFLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKLS
LKFRMGITISPVSHRLCAVPQV
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| BDBM50319983 |
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| n/a |
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| Name | BDBM50319983 |
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| Synonyms: | 3-(pyridin-4-yl)-N-(2-(trifluoromethoxy)benzyl)pyrrolidine-1-carboxamide | CHEMBL1085745 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H18F3N3O2 |
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| Mol. Mass. | 365.3496 |
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| SMILES | FC(F)(F)Oc1ccccc1CNC(=O)N1CCC(C1)c1ccncc1 |
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| Structure | 
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