| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
|---|
| Ligand | BDBM50374598 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_834667 (CHEMBL2072553) |
|---|
| Ki | 1.3±n/a nM |
|---|
| Citation |  Moussa, IA; Banister, SD; Manoli, M; Doddareddy, MR; Cui, J; Mach, RH; Kassiou, M Exploration of ring size in a series of cyclic vicinal diamines withs1 receptor affinity. Bioorg Med Chem Lett22:5493-7 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Sigma non-opioid intracellular receptor 1 |
|---|
| Name: | Sigma non-opioid intracellular receptor 1 |
|---|
| Synonyms: | Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 25266.54 |
|---|
| Organism: | RAT |
|---|
| Description: | Q9R0C9 |
|---|
| Residue: | 223 |
|---|
| Sequence: | MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRY
WAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
|
|
|
|---|
| BDBM50374598 |
|---|
| n/a |
|---|
| Name | BDBM50374598 |
|---|
| Synonyms: | CHEMBL272603 | US9604926, Compound CM-156 | US9724435, Compound CM-156 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H31N3S2 |
|---|
| Mol. Mass. | 389.621 |
|---|
| SMILES | S=c1sc2ccccc2n1CCCCN1CCN(CC1)C1CCCCC1 |
|---|
| Structure | 
|
|---|
Search and Browse
