| Reaction Details |
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 | Report a problem with these data |
| Target | Cytochrome P450 1B1 |
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| Ligand | BDBM50390436 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_834267 (CHEMBL2073034) |
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| IC50 | 900±n/a nM |
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| Citation |  Mikstacka, R; Rimando, AM; Dutkiewicz, Z; Stefanski, T; Sobiak, S Design, synthesis and evaluation of the inhibitory selectivity of novel trans-resveratrol analogues on human recombinant CYP1A1, CYP1A2 and CYP1B1. Bioorg Med Chem20:5117-26 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytochrome P450 1B1 |
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| Name: | Cytochrome P450 1B1 |
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| Synonyms: | CP1B1_HUMAN | CYP1B1 | CYPIB1 | Cytochrome P450 1B1 (CYP1B1) |
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| Type: | PROTEIN |
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| Mol. Mass.: | 60861.81 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1474523 |
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| Residue: | 543 |
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| Sequence: | MGTSLSPNDPWPLNPLSIQQTTLLLLLSVLATVHVGQRLLRQRRRQLRSAPPGPFAWPLI
GNAAAVGQAAHLSFARLARRYGDVFQIRLGSCPIVVLNGERAIHQALVQQGSAFADRPAF
ASFRVVSGGRSMAFGHYSEHWKVQRRAAHSMMRNFFTRQPRSRQVLEGHVLSEARELVAL
LVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYSHDDPEFRELLSHNEEFGRTVGAGSL
VDVMPWLQYFPNPVRTVFREFEQLNRNFSNFILDKFLRHCESLRPGAAPRDMMDAFILSA
EKKAAGDSHGGGARLDLENVPATITDIFGASQDTLSTALQWLLLLFTRYPDVQTRVQAEL
DQVVGRDRLPCMGDQPNLPYVLAFLYEAMRFSSFVPVTIPHATTANTSVLGYHIPKDTVV
FVNQWSVNHDPLKWPNPENFDPARFLDKDGLINKDLTSRVMIFSVGKRRCIGEELSKMQL
FLFISILAHQCDFRANPNEPAKMNFSYGLTIKPKSFKVNVTLRESMELLDSAVQNLQAKE
TCQ
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| BDBM50390436 |
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| n/a |
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| Name | BDBM50390436 |
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| Synonyms: | CHEMBL2071351 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H20O3S |
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| Mol. Mass. | 316.415 |
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| SMILES | COc1cc(OC)c(\C=C\c2ccc(SC)cc2)cc1OC |
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| Structure | 
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