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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | ATP-binding cassette sub-family C member 2 | ||
| Ligand | BDBM50329850 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_836182 (CHEMBL2075081) | ||
| Ki | 84100±n/a nM | ||
| Citation |  Akhteruzzaman, S; Kato, Y; Hisaka, A; Sugiyama, Y Primary active transport of peptidic endothelin antagonists by rat hepatic canalicular membrane. J Pharmacol Exp Ther288:575-81 (1999) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| ATP-binding cassette sub-family C member 2 | |||
| Name: | ATP-binding cassette sub-family C member 2 | ||
| Synonyms: | ATP-binding cassette sub-family C member 2 | Abcc2 | Canalicular multidrug resistance protein | Canalicular multispecific organic anion transporter 1 | Cmoat | Cmrp | MRP2_RAT | Mrp2 | Multidrug resistance-associated protein 2 | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 173415.22 | ||
| Organism: | Rattus norvegicus | ||
| Description: | ChEMBL_1455464 | ||
| Residue: | 1541 | ||
| Sequence: |
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| BDBM50329850 | |||
| n/a | |||
| Name | BDBM50329850 | ||
| Synonyms: | (R)-3-Amino-4-[(S)-2-((R)-1-{(S)-1-[(R)-1-(1H-indol-3-ylmethyl)-2-oxo-ethylcarbamoyl]-3-methyl-but-3-enylcarbamoyl}-2-methyl-propylcarbamoyl)-pyrrolidin-1-yl]-4-oxo-butyric acid | 2-((3R,6S,9R,12S,17aS)-9-((1H-indol-3-yl)methyl)-6-isobutyl-3-isopropyl-1,4,7,10,13-pentaoxohexadecahydro-1H-pyrrolo[1,2-a][1,4,7,10,13]pentaazacyclopentadecin-12-yl)acetic acid | CHEMBL1269102 | [(1S,4R,5R)-8-(1H-Indol-3-ylmethyl)-11-((S)-isobutyl)-14-((R)-isopropyl)-4,7,10,13,16-pentaoxo-hexadecahydro-3a,6,9,12,15-pentaaza-cyclopentacyclopentadecen-5-yl]-acetic acid | [(5R,8R,11S,14R,16aR)-8-(1H-Indol-3-ylmethyl)-11-isobutyl-14-isopropyl-4,7,10,13,16-pentaoxo-hexadecahydro-3a,6,9,12,15-pentaaza-cyclopentacyclopentadecen-5-yl]-acetic acid | [(5R,8R,11S,14R,16aS)-8-(1H-Indol-3-ylmethyl)-11-isobutyl-14-isopropyl-4,7,10,13,16-pentaoxo-hexadecahydro-3a,6,9,12,15-pentaaza-cyclopentacyclopentadecen-5-yl]-acetic acid | [8-(1H-Indol-3-ylmethyl)-11-isobutyl-14-isopropyl-4,7,10,13,16-pentaoxo-hexadecahydro-3a,6,9,12,15-pentaaza-cyclopentacyclopentadecen-5-yl]-acetic acid | ||
| Type | Small organic molecule | ||
| Emp. Form. | C31H42N6O7 | ||
| Mol. Mass. | 610.7012 | ||
| SMILES | CC(C)C[C@@H]1NC(=O)[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(O)=O)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC1=O)C(C)C |r| | ||
| Structure | 
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