Ki Summary

Reaction Details

Report a problem with these data

Target

Solute carrier family 22 member 6

Ligand

BDBM50270009

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_835925 (CHEMBL2077063)

500000±n/a nM

Citation

Jariyawat, S; Sekine, T; Takeda, M; Apiwattanakul, N; Kanai, Y; Sophasan, S; Endou, H The interaction and transport of beta-lactam antibiotics with the cloned rat renal organic anion transporter 1. J Pharmacol Exp Ther290:672-7 (1999) [PubMed]

More Info.:

Get all data from this article, Assay Method

Solute carrier family 22 member 6

Name:

Solute carrier family 22 member 6

Synonyms:

Type:

PROTEIN

Mol. Mass.:

60784.17

Organism:

Rattus norvegicus

Description:

ChEMBL_838479

Residue:

551

Sequence:

MAFNDLLKQVGGVGRFQLIQVTMVVAPLLLMASHNTLQNFTAAIPPHHCRPPANANLSKD
GGLEAWLPLDKQGQPESCLRFTSPQWGPPFYNGTEANGTRVTEPCIDGWVYDNSTFPSTI
VTEWNLVCSHRAFRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAA
YAPNYTVYCVFRLLSGMSLASIAINCMTLNVEWMPIHTRAYVGTLIGYVYSLGQFLLAGI
AYAVPHWRHLQLVVSVPFFIAFIYSWFFIESARWYSSSGRLDLTLRALQRVARINGKQEE
GAKLSIEVLRTSLQKELTLSKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDL
QGFGVSMYLIQVIFGAVDLPAKFVCFLVINSMGRRPAQMASLLLAGICILVNGIIPKSHT
IIRTSLAVLGKGCLASSFNCIFLYTGELYPTVIRQTGLGMGSTMARVGSIVSPLVSMTAE
FYPSMPLFIFGAVPVVASAVTALLPETLGQPLPDTVQDLKSRSRGKQNQQQQEQQKQMMP
LQASTQEKNGL

BDBM50270009

n/a

Name

BDBM50270009

Synonyms:

(2S,5R,6R)-6-{[carboxylato(phenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate | 6beta-(2-carboxylato-2-phenylacetamido)-2,2-dimethylpenam-3alpha-carboxylate | CARBENICILLIN | CARBENICILLIN DISODIUM | carbenicillin(2-)

Type

Small organic molecule

Emp. Form.

C17H16N2O6S

Mol. Mass.

376.385

SMILES

CC1(C)S[C@@H]2[C@H](NC(=O)C(C([O-])=O)c3ccccc3)C(=O)N2[C@H]1C([O-])=O |r|

Structure