| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 22 member 6 |
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| Ligand | BDBM50350473 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_835925 (CHEMBL2077063) |
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| Ki | 2330000±n/a nM |
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| Citation |  Jariyawat, S; Sekine, T; Takeda, M; Apiwattanakul, N; Kanai, Y; Sophasan, S; Endou, H The interaction and transport of beta-lactam antibiotics with the cloned rat renal organic anion transporter 1. J Pharmacol Exp Ther290:672-7 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier family 22 member 6 |
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| Name: | Solute carrier family 22 member 6 |
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| Synonyms: | Oat1 | Organic anion transporter 1 | S22A6_RAT | Slc22a6 | rOAT1 | rROAT1 | renal organic anion transporter 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 60784.17 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_838479 |
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| Residue: | 551 |
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| Sequence: | MAFNDLLKQVGGVGRFQLIQVTMVVAPLLLMASHNTLQNFTAAIPPHHCRPPANANLSKD
GGLEAWLPLDKQGQPESCLRFTSPQWGPPFYNGTEANGTRVTEPCIDGWVYDNSTFPSTI
VTEWNLVCSHRAFRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAA
YAPNYTVYCVFRLLSGMSLASIAINCMTLNVEWMPIHTRAYVGTLIGYVYSLGQFLLAGI
AYAVPHWRHLQLVVSVPFFIAFIYSWFFIESARWYSSSGRLDLTLRALQRVARINGKQEE
GAKLSIEVLRTSLQKELTLSKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDL
QGFGVSMYLIQVIFGAVDLPAKFVCFLVINSMGRRPAQMASLLLAGICILVNGIIPKSHT
IIRTSLAVLGKGCLASSFNCIFLYTGELYPTVIRQTGLGMGSTMARVGSIVSPLVSMTAE
FYPSMPLFIFGAVPVVASAVTALLPETLGQPLPDTVQDLKSRSRGKQNQQQQEQQKQMMP
LQASTQEKNGL
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| BDBM50350473 |
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| n/a |
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| Name | BDBM50350473 |
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| Synonyms: | Aliporina | CEFALORIDINE |
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| Type | Small organic molecule |
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| Emp. Form. | C19H17N3O4S2 |
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| Mol. Mass. | 415.486 |
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| SMILES | [O-]C(=O)C1=C(C[n+]2ccccc2)CS[C@@H]2[C@@H](NC(=O)Cc3cccs3)C(=O)N12 |r,c:3| |
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| Structure | 
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