| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 22 member 8 |
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| Ligand | BDBM50367502 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_835944 (CHEMBL2077082) |
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| IC50 | 742000±n/a nM |
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| Citation |  Khamdang, S; Takeda, M; Shimoda, M; Noshiro, R; Narikawa, S; Huang, XL; Enomoto, A; Piyachaturawat, P; Endou, H Interactions of human- and rat-organic anion transporters with pravastatin and cimetidine. J Pharmacol Sci94:197-202 (2004) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier family 22 member 8 |
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| Name: | Solute carrier family 22 member 8 |
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| Synonyms: | Oat3 | Organic anion transporter 3 | S22A8_RAT | Slc22a8 | rOat3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 59199.83 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1482580 |
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| Residue: | 536 |
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| Sequence: | MTFSEILDRVGSMGPFQYLHVTLLALPVLGIANHNLLQIFTATTPVHHCRPPPNASIGPW
VLPLDPNGKPEKCLRFVHLPNASLPNDTQRATEPCLDGWIYNSTRDTIVIEWDLVCSSNK
LKEMAQSIFMAGILVGGPVIGELSDRFGRKPILTWSYLMLAASGSGAAFSPSLPVYMIFR
FLCGCSISGISLSTVILNVEWVPTSMRAISSTSIGYCYTIGQFILSGLAYAIPQWRWLQL
TSSAPFFIFSLLSWWVPESIRWLVLSGKYSKALKTLQRVATFNGKKEEGKKLTIEELKFN
LQKDITSAKVKYGLSDLFRVSILRRVTFCLSLAWFSTGFAYYSLAMGVEEFGVNIYILQI
IFGGVDIPAKFITILSLSYLGRRITQSFLLLLAGGAILALIFVPSEMQLLRTALAVFGKG
CLSGSFSCLFLYTSELYPTVLRQTGMGISNVWARVGSMIAPLVKITGELQPFIPNVIFGT
TALLGGSAAFFLLETLNRPLPETIEDIQNWHKQVQKTKQESEAEKASQIIPLKTGG
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| BDBM50367502 |
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| n/a |
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| Name | BDBM50367502 |
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| Synonyms: | CILASTATIN |
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| Type | Small organic molecule |
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| Emp. Form. | C16H26N2O5S |
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| Mol. Mass. | 358.453 |
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| SMILES | CC1(C)C[C@@H]1C(=O)N\C(=C/CCCCSC[C@H](N)C(O)=O)C(O)=O |r| |
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| Structure | 
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