| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Solute carrier family 22 member 6 |
|---|
| Ligand | BDBM50367502 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_837478 (CHEMBL2075966) |
|---|
| IC50 | 2387000±n/a nM |
|---|
| Citation |  Khamdang, S; Takeda, M; Shimoda, M; Noshiro, R; Narikawa, S; Huang, XL; Enomoto, A; Piyachaturawat, P; Endou, H Interactions of human- and rat-organic anion transporters with pravastatin and cimetidine. J Pharmacol Sci94:197-202 (2004) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Solute carrier family 22 member 6 |
|---|
| Name: | Solute carrier family 22 member 6 |
|---|
| Synonyms: | Oat1 | Organic anion transporter 1 | S22A6_RAT | Slc22a6 | rOAT1 | rROAT1 | renal organic anion transporter 1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 60784.17 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_838479 |
|---|
| Residue: | 551 |
|---|
| Sequence: | MAFNDLLKQVGGVGRFQLIQVTMVVAPLLLMASHNTLQNFTAAIPPHHCRPPANANLSKD
GGLEAWLPLDKQGQPESCLRFTSPQWGPPFYNGTEANGTRVTEPCIDGWVYDNSTFPSTI
VTEWNLVCSHRAFRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAA
YAPNYTVYCVFRLLSGMSLASIAINCMTLNVEWMPIHTRAYVGTLIGYVYSLGQFLLAGI
AYAVPHWRHLQLVVSVPFFIAFIYSWFFIESARWYSSSGRLDLTLRALQRVARINGKQEE
GAKLSIEVLRTSLQKELTLSKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDL
QGFGVSMYLIQVIFGAVDLPAKFVCFLVINSMGRRPAQMASLLLAGICILVNGIIPKSHT
IIRTSLAVLGKGCLASSFNCIFLYTGELYPTVIRQTGLGMGSTMARVGSIVSPLVSMTAE
FYPSMPLFIFGAVPVVASAVTALLPETLGQPLPDTVQDLKSRSRGKQNQQQQEQQKQMMP
LQASTQEKNGL
|
|
|
|---|
| BDBM50367502 |
|---|
| n/a |
|---|
| Name | BDBM50367502 |
|---|
| Synonyms: | CILASTATIN |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H26N2O5S |
|---|
| Mol. Mass. | 358.453 |
|---|
| SMILES | CC1(C)C[C@@H]1C(=O)N\C(=C/CCCCSC[C@H](N)C(O)=O)C(O)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
