| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier organic anion transporter family member 1A2 |
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| Ligand | BDBM50370232 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_837096 (CHEMBL2076348) |
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| Ki | 51000±n/a nM |
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| Citation |  Vavricka, SR; Van Montfoort, J; Ha, HR; Meier, PJ; Fattinger, K Interactions of rifamycin SV and rifampicin with organic anion uptake systems of human liver. Hepatology36:164-72 (2002) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier organic anion transporter family member 1A2 |
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| Name: | Solute carrier organic anion transporter family member 1A2 |
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| Synonyms: | OATP | OATP-1 | OATP-A | OATP1 | OATP1A2 | Organic anion-transporting polypeptide 1 | SLC21A3 | SLCO1A2 | SO1A2_HUMAN | Sodium-independent organic anion transporter | Solute carrier family 21 member 3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 74140.62 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_837096 |
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| Residue: | 670 |
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| Sequence: | MGETEKRIETHRIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGF
INGSFEIGNLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVS
VSGNLSSNSFLCMENGTQILRPTQDPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGI
SYIEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTR
WVGAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLETNADIIKNENEDKQKEEVKKEKYG
ITKDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGI
YNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINT
SYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETSIGTGINMV
FQNCSCIQTSGNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMK
SEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYI
YLGLPAALRGSSFVPALIILILLRKCHLPGENASSGTELIETKVKGKENECKDIYQKSTV
LKDDELKTKL
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| BDBM50370232 |
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| n/a |
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| Name | BDBM50370232 |
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| Synonyms: | BA-41166E | L-5103 | RIFAMPIN | Rifadin | Rifampicin |
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| Type | Small organic molecule |
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| Emp. Form. | C43H58N4O12 |
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| Mol. Mass. | 822.9402 |
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| SMILES | CO[C@H]1\C=C\O[C@@]2(C)Oc3c(C2=O)c2c(O)c(\C=N\N4CCN(C)CC4)c(NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)c(O)c2c(O)c3C |r,c:33,t:3,35| |
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| Structure | 
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