| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM50391586 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_850393 (CHEMBL2150813) |
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| Ki | 343.3±n/a nM |
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| Citation |  Ida, Y; Matsubara, A; Nemoto, T; Saito, M; Hirayama, S; Fujii, H; Nagase, H Synthesis of quinolinomorphinan derivatives as highly selectived opioid receptor ligands. Bioorg Med Chem20:5810-31 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | Kappa Opioid Receptor | OPIATE Kappa | OPRK1 | OPRK_CAVPO | Opiate Kappa 1 | mu/kappa opioid receptor |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42744.99 |
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| Organism: | Cavia porcellus (domestic guinea pig) |
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| Description: | P41144 |
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| Residue: | 380 |
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| Sequence: | MGRRRQGPAQPASELPARNACLLPNGSAWLPGWAEPDGNGSAGPQDEQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIILGGTKVREDVDIIECSLQFPDDDYSWWDLFMKICVFVFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRV
RNTVQDPAYMRNVDGVNKPV
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| BDBM50391586 |
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| n/a |
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| Name | BDBM50391586 |
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| Synonyms: | CHEMBL2147931 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H29N3O2 |
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| Mol. Mass. | 415.5274 |
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| SMILES | CN(C)c1cccc2cc3C[C@@]4(O)[C@H]5Cc6ccc(O)cc6[C@@]4(CCN5C)Cc3nc12 |r,THB:26:25:11:21.15.14| |
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| Structure | 
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