| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 22 member 2 |
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| Ligand | BDBM50062614 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_852936 (CHEMBL2154120) |
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| IC50 | 2500±n/a nM |
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| Citation |  Kido, Y; Matsson, P; Giacomini, KM Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2. J Med Chem54:4548-58 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier family 22 member 2 |
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| Name: | Solute carrier family 22 member 2 |
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| Synonyms: | OCT2 | Organic cation transporter 2 | S22A2_HUMAN | SLC22A2 | hOCT2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 62591.01 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1484077 |
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| Residue: | 555 |
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| Sequence: | MPTTVDDVLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLGFTPDHRCRSPGVAELS
LRCGWSPAEELNYTVPGPGPAGEASPRQCRRYEVDWNQSTFDCVDPLASLDTNRSRLPLG
PCRDGWVYETPGSSIVTEFNLVCANSWMLDLFQSSVNVGFFIGSMSIGYIADRFGRKLCL
LTTVLINAAAGVLMAISPTYTWMLIFRLIQGLVSKAGWLIGYILITEFVGRRYRRTVGIF
YQVAYTVGLLVLAGVAYALPHWRWLQFTVSLPNFFFLLYYWCIPESPRWLISQNKNAEAM
RIIKHIAKKNGKSLPASLQRLRLEEETGKKLNPSFLDLVRTPQIRKHTMILMYNWFTSSV
LYQGLIMHMGLAGDNIYLDFFYSALVEFPAAFMIILTIDRIGRRYPWAASNMVAGAACLA
SVFIPGDLQWLKIIISCLGRMGITMAYEIVCLVNAELYPTFIRNLGVHICSSMCDIGGII
TPFLVYRLTNIWLELPLMVFGVLGLVAGGLVLLLPETKGKALPETIEEAENMQRPRKNKE
KMIYLQVQKLDIPLN
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| BDBM50062614 |
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| n/a |
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| Name | BDBM50062614 |
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| Synonyms: | CHEMBL900 | Dimethyl-[2-(phenyl-o-tolyl-methoxy)-ethyl]-amine | Disipal | Invagesic | N,N-dimethyl-2-(phenyl(o-tolyl)methoxy)ethanamine | Norflex | Norgesic | ORPHENADRINE | Orphengesic |
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| Type | Small organic molecule |
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| Emp. Form. | C18H23NO |
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| Mol. Mass. | 269.3813 |
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| SMILES | CN(C)CCOC(c1ccccc1)c1ccccc1C |
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| Structure | 
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