| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
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| Ligand | BDBM50395160 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_859794 (CHEMBL2169622) |
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| Ki | 476±n/a nM |
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| Citation |  Baraldi, PG; Saponaro, G; Moorman, AR; Romagnoli, R; Preti, D; Baraldi, S; Ruggiero, E; Varani, K; Targa, M; Vincenzi, F; Borea, PA; Aghazadeh Tabrizi, M 7-Oxo-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxamides as selective CB(2) cannabinoid receptor ligands: structural investigations around a novel class of full agonists. J Med Chem55:6608-23 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 1 |
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| Name: | Cannabinoid receptor 1 |
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| Synonyms: | Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_RAT | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cnr1 | Skr6 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 52856.55 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P20272 |
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| Residue: | 473 |
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| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEENIQCGENFMDMECFMILNPSQQLAI
AVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHV
FHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCL
MWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILW
KAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPL
LAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTA
QPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
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| BDBM50395160 |
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| n/a |
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| Name | BDBM50395160 |
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| Synonyms: | CHEMBL2163938 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H34N2O3 |
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| Mol. Mass. | 434.5705 |
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| SMILES | CCCC1COc2cccc3c2n1cc(C(=O)NC12CC4CC(C)(CC(C)(C4)C1)C2)c3=O |TLB:27:25:29:21.20.19,27:20:24.25.28:29,26:25:29:21.20.19,THB:19:20:24:28.18.29,19:18:24:21.27.20| |
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| Structure | 
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