| Reaction Details |
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 | Report a problem with these data |
| Target | Betaine--homocysteine S-methyltransferase 1 |
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| Ligand | BDBM50395382 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_857980 (CHEMBL2166488) |
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| IC50 | 76600±n/a nM |
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| Citation |  Mládková, J; Vanek, V; Budešínský, M; Elbert, T; Demianová, Z; Garrow, TA; Jirácek, J Double-headed sulfur-linked amino acids as first inhibitors for betaine-homocysteine S-methyltransferase 2. J Med Chem55:6822-31 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Betaine--homocysteine S-methyltransferase 1 |
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| Name: | Betaine--homocysteine S-methyltransferase 1 |
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| Synonyms: | BHMT | BHMT1_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 45000.99 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_970672 |
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| Residue: | 406 |
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| Sequence: | MPPVGGKKAKKGILERLNAGEIVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLH
REFLRAGSNVMQTFTFYASEDKLENRGNYVLEKISGQEVNEAACDIARQVADEGDALVAG
GVSQTPSYLSCKSETEVKKVFLQQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKP
VAATMCIGPEGDLHGVPPGECAVRLVKAGASIIGVNCHFDPTISLKTVKLMKEGLEAARL
KAHLMSQPLAYHTPDCNKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCC
GFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWVRARARKEYWENLRIASG
RPYNPSMSKPDGWGVTKGTAELMQQKEATTEQQLKELFEKQKFKSQ
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| BDBM50395382 |
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| n/a |
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| Name | BDBM50395382 |
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| Synonyms: | CHEMBL2164724 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H24N2O4S |
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| Mol. Mass. | 292.395 |
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| SMILES | CC(CCSCC[C@H](N)C(O)=O)CCC(N)C(O)=O |r| |
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| Structure | 
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