| Reaction Details |
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 | Report a problem with these data |
| Target | Serine protease SplB |
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| Ligand | BDBM50395592 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_859707 (CHEMBL2169142) |
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| Ki | 12000±n/a nM |
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| Citation |  Ewa, B; Maciej, W; Marcin, S; Grzegorz, D; Michal, Z; Jan, P; Józef, O The development of first Staphylococcus aureus SplB protease inhibitors: phosphonic analogues of glutamine. Bioorg Med Chem Lett22:5574-8 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine protease SplB |
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| Name: | Serine protease SplB |
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| Synonyms: | SPLB_STAAU | splB |
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| Type: | PROTEIN |
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| Mol. Mass.: | 26147.73 |
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| Organism: | Staphylococcus aureus |
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| Description: | ChEMBL_859707 |
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| Residue: | 240 |
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| Sequence: | MNKNVVIKSLATLTILTSVTGIGTTLVEEVQQTAKAENNVTKIQDTNIFPYTGVVAFKSA
TGFVVGKNTILTNKHVSKNYKVGDRITAHPNSDKGNGGIYSIKKIINYPGKEDVSVIQVE
ERAIERGPKGFNFNDNVTPFKYAAGAKAGERIKVIGYPHPYKNKYVLYESTGPVMSVEGS
SIVYSAHTESGNSGSPVLNSNNELVGIHFASDVKNDDNRNAYGVYFTPEIKKFIAENIDK
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| BDBM50395592 |
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| n/a |
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| Name | BDBM50395592 |
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| Synonyms: | CHEMBL2165312 |
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| Type | Small organic molecule |
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| Emp. Form. | C39H52N5O9P |
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| Mol. Mass. | 765.832 |
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| SMILES | CCc1ccc(OP(=O)(Oc2ccc(CC)cc2)C(CCC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(CCC(N)=O)NC(=O)OCc2ccccc2)cc1 |
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| Structure | 
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