| Reaction Details |
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 | Report a problem with these data |
| Target | Cell division related protein kinase 2 |
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| Ligand | BDBM47658 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_862287 (CHEMBL2173143) |
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| IC50 | 1500±n/a nM |
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| Citation |  Rotella, DP Recent results in protein kinase inhibition for tropical diseases. Bioorg Med Chem Lett22:6788-93 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cell division related protein kinase 2 |
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| Name: | Cell division related protein kinase 2 |
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| Synonyms: | CRK3 | Cdc2-related kinase | Cell division related protein kinase 2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 35647.04 |
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| Organism: | Leishmania major |
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| Description: | ChEMBL_862288 |
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| Residue: | 311 |
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| Sequence: | MSSFGRVTARSGDAGTRDSLDRYNRLDVLGEGTYGVVYRAVDKITGQYVALKKVRLDRTE
EGIPQTALREVSILQEFDHPNIVNLLDVICSDGKLYLVFEYVEADLKKAIEKQEGGYSGM
DLKRLIYQLLDGLYFCHRHRIIHRDLKPANILLTSGNVLKLADFGLARAFQVPMHTYTHE
VVTLWYRAPEILLGEKHYTPAVDMWSVGCIFAELTRRKVLFRGDSEIGQLFEIFQVLGTP
TDTEGSWPGVSRLPDYRDVFPKWTAKRLGQVLPELHPDAIDLLSKMLKYDPRERISAKEA
LQHPWFSDLRW
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| BDBM47658 |
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| n/a |
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| Name | BDBM47658 |
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| Synonyms: | 1-(4-methylphenyl)-3-(2-pyridin-3-ylpyrimidin-4-yl)urea | 1-(4-methylphenyl)-3-[2-(3-pyridinyl)-4-pyrimidinyl]urea | 1-(p-tolyl)-3-[2-(3-pyridyl)pyrimidin-4-yl]urea | MLS000706883 | N-(4-methylphenyl)-N'-[2-(3-pyridinyl)-4-pyrimidinyl]urea | SMR000335712 | cid_1477566 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H15N5O |
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| Mol. Mass. | 305.3339 |
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| SMILES | Cc1ccc(NC(=O)Nc2ccnc(n2)-c2cccnc2)cc1 |
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| Structure | 
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