| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cyclin-dependent kinase 2 |
|---|
| Ligand | BDBM50321461 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_862291 (CHEMBL2173147) |
|---|
| IC50 | >20000±n/a nM |
|---|
| Citation |  Rotella, DP Recent results in protein kinase inhibition for tropical diseases. Bioorg Med Chem Lett22:6788-93 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cyclin-dependent kinase 2 |
|---|
| Name: | Cyclin-dependent kinase 2 |
|---|
| Synonyms: | CDK2 | CDK2-Kinase | CDK2_HUMAN | CDKN2 | Cell division protein kinase 2 | Cyclin-dependent kinase 2 (CDK2) | Protein cereblon/Cyclin-dependent kinase 2 | p33 protein kinase |
|---|
| Type: | Enzyme Subunit |
|---|
| Mol. Mass.: | 33938.17 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P24941 |
|---|
| Residue: | 298 |
|---|
| Sequence: | MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH
PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS
HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY
STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF
PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
|
|
|
|---|
| BDBM50321461 |
|---|
| n/a |
|---|
| Name | BDBM50321461 |
|---|
| Synonyms: | 2-bromo-N-(2,5-dichlorothiophen-3-ylsulfonyl)-N-phenylacetamide | CHEMBL1171238 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H8BrCl2NO3S2 |
|---|
| Mol. Mass. | 429.137 |
|---|
| SMILES | Clc1cc(c(Cl)s1)S(=O)(=O)N(C(=O)CBr)c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
