| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50374600 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_873469 (CHEMBL2186564) |
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| Ki | 1.7±n/a nM |
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| Citation |  James, ML; Shen, B; Zavaleta, CL; Nielsen, CH; Mesangeau, C; Vuppala, PK; Chan, C; Avery, BA; Fishback, JA; Matsumoto, RR; Gambhir, SS; McCurdy, CR; Chin, FT New positron emission tomography (PET) radioligand for imagings-1 receptors in living subjects. J Med Chem55:8272-82 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25266.54 |
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| Organism: | RAT |
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| Description: | Q9R0C9 |
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| Residue: | 223 |
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| Sequence: | MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRY
WAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
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| BDBM50374600 |
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| n/a |
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| Name | BDBM50374600 |
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| Synonyms: | CHEMBL272899 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H26N2OS |
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| Mol. Mass. | 318.477 |
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| SMILES | CCCc1ccc2n(CCN3CCCCCC3)c(=O)sc2c1 |
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| Structure | 
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