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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Estrogen receptor | ||
| Ligand | BDBM50398942 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_874808 (CHEMBL2188852) | ||
| EC50 | 600±n/a nM | ||
| Citation |  Schäfer, A; Wellner, A; Strauss, M; Schäfer, A; Wolber, G; Gust, R Influence of chlorine or fluorine substitution on the estrogenic properties of 1-alkyl-2,3,5-tris(4-hydroxyphenyl)-1H-pyrroles. J Med Chem55:9607-18 (2012) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Estrogen receptor | |||
| Name: | Estrogen receptor | ||
| Synonyms: | ER | ER-alpha | ESR | ESR1 | ESR1_HUMAN | Estradiol receptor | Estrogen receptor | Estrogen receptor (ER alpha) | Estrogen receptor (ER-alpha) | Estrogen receptor alpha (ER alpha) | Estrogen receptor alpha (ER) | NR3A1 | Nuclear receptor subfamily 3 group A member 1 | ||
| Type: | Protein | ||
| Mol. Mass.: | 66230.44 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P03372 | ||
| Residue: | 595 | ||
| Sequence: |
| ||
| BDBM50398942 | |||
| n/a | |||
| Name | BDBM50398942 | ||
| Synonyms: | CHEMBL2179252 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H18ClNO3 | ||
| Mol. Mass. | 391.847 | ||
| SMILES | Cn1c(cc(c1-c1ccc(O)cc1Cl)-c1ccc(O)cc1)-c1ccc(O)cc1 |(16.91,-23.7,;16.58,-22.2,;15.18,-21.58,;15.33,-20.05,;16.84,-19.72,;17.61,-21.05,;19.14,-21.2,;20.03,-19.96,;21.56,-20.11,;22.2,-21.52,;23.73,-21.67,;21.3,-22.77,;19.77,-22.61,;18.87,-23.86,;17.46,-18.32,;18.99,-18.15,;19.61,-16.74,;18.7,-15.5,;19.32,-14.09,;17.16,-15.67,;16.55,-17.08,;13.84,-22.35,;12.5,-21.59,;11.17,-22.36,;11.17,-23.9,;9.84,-24.67,;12.51,-24.68,;13.84,-23.9,)| | ||
| Structure | 
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