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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Estrogen receptor | ||
| Ligand | BDBM50398941 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_874806 (CHEMBL2188850) | ||
| EC50 | 0.31±n/a nM | ||
| Citation |  Schäfer, A; Wellner, A; Strauss, M; Schäfer, A; Wolber, G; Gust, R Influence of chlorine or fluorine substitution on the estrogenic properties of 1-alkyl-2,3,5-tris(4-hydroxyphenyl)-1H-pyrroles. J Med Chem55:9607-18 (2012) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Estrogen receptor | |||
| Name: | Estrogen receptor | ||
| Synonyms: | ER | ER-alpha | ESR | ESR1 | ESR1_HUMAN | Estradiol receptor | Estrogen receptor | Estrogen receptor (ER alpha) | Estrogen receptor (ER-alpha) | Estrogen receptor alpha (ER alpha) | Estrogen receptor alpha (ER) | NR3A1 | Nuclear receptor subfamily 3 group A member 1 | ||
| Type: | Protein | ||
| Mol. Mass.: | 66230.44 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P03372 | ||
| Residue: | 595 | ||
| Sequence: |
| ||
| BDBM50398941 | |||
| n/a | |||
| Name | BDBM50398941 | ||
| Synonyms: | CHEMBL2179253 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C25H22ClNO3 | ||
| Mol. Mass. | 419.9 | ||
| SMILES | CCCn1c(cc(c1-c1ccc(O)cc1Cl)-c1ccc(O)cc1)-c1ccc(O)cc1 |(31.93,-24.98,;31.61,-23.47,;32.75,-22.44,;32.42,-20.93,;31.01,-20.31,;31.17,-18.78,;32.67,-18.45,;33.45,-19.78,;34.97,-19.94,;35.87,-18.69,;37.4,-18.84,;38.04,-20.25,;39.57,-20.4,;37.13,-21.5,;35.6,-21.34,;34.7,-22.59,;33.29,-17.05,;34.82,-16.88,;35.45,-15.48,;34.54,-14.23,;35.15,-12.82,;33,-14.41,;32.38,-15.81,;29.67,-21.09,;28.34,-20.32,;27.01,-21.09,;27.01,-22.64,;25.67,-23.41,;28.34,-23.41,;29.68,-22.64,)| | ||
| Structure | 
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