| Reaction Details |
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 | Report a problem with these data |
| Target | Monoglyceride lipase |
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| Ligand | BDBM50399281 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_877097 (CHEMBL2186833) |
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| IC50 | 427.1±n/a nM |
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| Citation |  Alapafuja, SO; Nikas, SP; Bharathan, IT; Shukla, VG; Nasr, ML; Bowman, AL; Zvonok, N; Li, J; Shi, X; Engen, JR; Makriyannis, A Sulfonyl fluoride inhibitors of fatty acid amide hydrolase. J Med Chem55:10074-89 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Monoglyceride lipase |
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| Name: | Monoglyceride lipase |
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| Synonyms: | HU-K5 | Lysophospholipase homolog | Lysophospholipase-like | MAGL | MGL | MGLL | MGLL_HUMAN |
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| Type: | Hydrolase |
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| Mol. Mass.: | 33264.56 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human recombinant MGL (Cayman Chemical, cat# 10008354). |
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| Residue: | 303 |
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| Sequence: | MPEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEE
LARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLG
HSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPID
SSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADR
LCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSVFHEINMWVSQRTATAGTA
SPP
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| BDBM50399281 |
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| n/a |
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| Name | BDBM50399281 |
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| Synonyms: | CHEMBL2180818 | US9102622, 14.1 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H19FO3S |
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| Mol. Mass. | 274.352 |
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| SMILES | Oc1ccc(CCCCCCCS(F)(=O)=O)cc1 |
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| Structure | 
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