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TargetCasein kinase I isoform epsilon
LigandBDBM50364141
Substrate/Competitorn/a
Meas. Tech.ChEMBL_878858 (CHEMBL2184571)
IC50 80±n/a nM
Citation Long, AMZhao, HHuang, X Structural basis for the potent and selective inhibition of casein kinase 1 epsilon. J Med Chem55:10307-11 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Casein kinase I isoform epsilon
Name:Casein kinase I isoform epsilon
Synonyms:Axin-1/Casein kinase I epsilon | CKI-epsilon | CKIe | CSNK1E | Casein kinase 1 epsilon (CK1Ɛ) | Casein kinase I epsilon | Casein kinase I isoform epsilon (CK1 epsilon) | Casein kinase I isoform epsilon (CK1E) | Casein kinase I isoform epsilon (CK1epsilon) | KC1E_HUMAN
Type:Protein
Mol. Mass.:47340.25
Organism:Homo sapiens (Human)
Description:P49674
Residue:416
Sequence:
MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQ
GGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
CKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGAARN
PEDVDRERREHEREERMGQLRGSATRALPPGPPTGATANRLRSAAEPVASTPASRIQPAG
NTSPRAISRVDRERKVSMRLHRGAPANVSSSDLTGRQEVSRIPASQTSVPFDHLGK
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  Blast E-value cutoff:
BDBM50364141
n/a
NameBDBM50364141
Synonyms:CHEMBL1951415
TypeSmall organic molecule
Emp. Form.C19H20FN5
Mol. Mass.337.394
SMILESNc1nccc(n1)-c1c(ncn1C1CCCCC1)-c1ccc(F)cc1
Structure
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