| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin S |
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| Ligand | BDBM50400188 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_878614 (CHEMBL2189084) |
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| IC50 | >100000±n/a nM |
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| Citation |  Moreira, DR; Costa, SP; Hernandes, MZ; Rabello, MM; de Oliveira Filho, GB; de Melo, CM; da Rocha, LF; de Simone, CA; Ferreira, RS; Fradico, JR; Meira, CS; Guimarães, ET; Srivastava, RM; Pereira, VR; Soares, MB; Leite, AC Structural investigation of anti-Trypanosoma cruzi 2-iminothiazolidin-4-ones allows the identification of agents with efficacy in infected mice. J Med Chem55:10918-36 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cathepsin S |
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| Name: | Cathepsin S |
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| Synonyms: | CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein |
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| Type: | Protein |
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| Mol. Mass.: | 37507.38 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P25774 |
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| Residue: | 331 |
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| Sequence: | MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVM
LHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVD
WREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGC
NGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKE
AVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSW
GHNFGEEGYIRMARNKGNHCGIASFPSYPEI
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| BDBM50400188 |
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| n/a |
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| Name | BDBM50400188 |
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| Synonyms: | CHEMBL2180670 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H21N3O2S |
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| Mol. Mass. | 319.422 |
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| SMILES | CC(C)c1sc(=NN=C(C)COc2ccccc2)n(C)c1O |w:7.6| |
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| Structure | 
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