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TargetCathepsin S
LigandBDBM50400190
Substrate/Competitorn/a
Meas. Tech.ChEMBL_878614 (CHEMBL2189084)
IC50>100000±n/a nM
Citation Moreira, DRCosta, SPHernandes, MZRabello, MMde Oliveira Filho, GBde Melo, CMda Rocha, LFde Simone, CAFerreira, RSFradico, JRMeira, CSGuimarães, ETSrivastava, RMPereira, VRSoares, MBLeite, AC Structural investigation of anti-Trypanosoma cruzi 2-iminothiazolidin-4-ones allows the identification of agents with efficacy in infected mice. J Med Chem55:10918-36 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Cathepsin S
Name:Cathepsin S
Synonyms:CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein
Type:Protein
Mol. Mass.:37507.38
Organism:Homo sapiens (Human)
Description:P25774
Residue:331
Sequence:
MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVM
LHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVD
WREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGC
NGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKE
AVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSW
GHNFGEEGYIRMARNKGNHCGIASFPSYPEI
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50400190
n/a
NameBDBM50400190
Synonyms:CHEMBL2180354
TypeSmall organic molecule
Emp. Form.C12H13N3O2S
Mol. Mass.263.316
SMILESCC(COc1ccccc1)N=Nc1nc(O)cs1 |w:10.10|
Structure
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