Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | D(2) dopamine receptor | ||
| Ligand | BDBM50115277 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_880027 (CHEMBL2213376) | ||
| EC50 | 41±n/a nM | ||
| Citation |  Gogoi, S; Biswas, S; Modi, G; Antonio, T; Reith, ME; Dutta, AK Novel bivalent ligands for D2/D3 dopamine receptors: Significant co-operative gain in D2 affinity and potency. ACS Med Chem Lett3:991-996 (2012) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| D(2) dopamine receptor | |||
| Name: | D(2) dopamine receptor | ||
| Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 | ||
| Type: | Cell-surface receptors | ||
| Mol. Mass.: | 50647.10 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P14416 | ||
| Residue: | 443 | ||
| Sequence: |
| ||
| BDBM50115277 | |||
| n/a | |||
| Name | BDBM50115277 | ||
| Synonyms: | (2R,3R)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol | (2R,3S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol | (2S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol | (2S,3R)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol | (S)-(-)-5-hydroxy-2-(N,N-di-n-propylamino)tetralin | (S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol | (S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol.HCl | 6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol | CHEMBL269004 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C16H25NO | ||
| Mol. Mass. | 247.3758 | ||
| SMILES | CCCN(CCC)[C@H]1CCc2c(O)cccc2C1 |r| | ||
| Structure | 
| ||