| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Histamine H2 receptor |
|---|
| Ligand | BDBM50400738 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_880414 (CHEMBL2210097) |
|---|
| Ki | 5157±n/a nM |
|---|
| Citation |  Yu, LF; Zhang, HK; Gunosewoyo, H; Kozikowski, AP From a4ß2 Nicotinic Ligands to the Discovery of s1 Receptor Ligands: Pharmacophore Analysis and Rational Design. ACS Med Chem Lett3:1054-1058 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Histamine H2 receptor |
|---|
| Name: | Histamine H2 receptor |
|---|
| Synonyms: | Gastric receptor I | H2R | HISTAMINE H2 | HRH2 | HRH2_HUMAN | Histamine H2 receptor | Histamine H2-Gs alpha S |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 40115.31 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 359 |
|---|
| Sequence: | MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSL
AITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV
MDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNE
VYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATIREHKATVTLAAVM
GAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQ
QLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGTEVTAPQGATDR
|
|
|
|---|
| BDBM50400738 |
|---|
| n/a |
|---|
| Name | BDBM50400738 |
|---|
| Synonyms: | CHEMBL2203551 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H18N2O3 |
|---|
| Mol. Mass. | 274.315 |
|---|
| SMILES | C(Oc1cc(COc2ccccc2)on1)[C@@H]1CCCN1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
