| Reaction Details |
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 | Report a problem with these data |
| Target | Cyclin-dependent kinase 1 |
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| Ligand | BDBM50400801 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_879215 (CHEMBL2208528) |
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| IC50 | 1.000±n/a nM |
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| Citation |  Marsault, E; Peterson, ML Macrocycles are great cycles: applications, opportunities, and challenges of synthetic macrocycles in drug discovery. J Med Chem54:1961-2004 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cyclin-dependent kinase 1 |
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| Name: | Cyclin-dependent kinase 1 |
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| Synonyms: | CDC2 | CDC28A | CDK1 | CDK1_HUMAN | CDKN1 | Cell division control protein 2 homolog | Cell division protein kinase 1 | Cyclin-dependent kinase 1 (CDK1) | P34CDC2 | p34 protein kinase |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 34101.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P06493 |
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| Residue: | 297 |
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| Sequence: | MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH
PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH
SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR
YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT
FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM
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| BDBM50400801 |
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| n/a |
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| Name | BDBM50400801 |
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| Synonyms: | CHEMBL215803 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H21N5O3 |
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| Mol. Mass. | 403.4338 |
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| SMILES | [H][C@]12C[C@@H](C)N(C1)CCn1nc3c(cccc3c1O)-c1nc3c(O2)cccc3nc1O |
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| Structure | 
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