| Reaction Details |
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 | Report a problem with these data |
| Target | D(1B) dopamine receptor |
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| Ligand | BDBM50400823 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_879321 (CHEMBL2208719) |
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| Ki | 16.6±n/a nM |
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| Citation |  Meanwell, NA Synopsis of some recent tactical application of bioisosteres in drug design. J Med Chem54:2529-91 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(1B) dopamine receptor |
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| Name: | D(1B) dopamine receptor |
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| Synonyms: | D(5) dopamine receptor | D1beta dopamine receptor | DOPAMINE D5 | DRD1B | DRD1L2 | DRD5 | DRD5_HUMAN | dopamine receptor D5 |
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| Type: | Protein |
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| Mol. Mass.: | 52943.41 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21918 |
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| Residue: | 477 |
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| Sequence: | MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVL
VCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGAFCDVWVAFD
IMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNW
HRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAI
MIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSV
IMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIYA
FNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTP
GNREVDNDEEEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH
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| BDBM50400823 |
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| n/a |
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| Name | BDBM50400823 |
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| Synonyms: | CHEMBL2204343 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H23ClFNO2Si |
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| Mol. Mass. | 391.939 |
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| SMILES | O[Si]1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 |
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| Structure | 
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