| Reaction Details |
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 | Report a problem with these data |
| Target | 3-oxoacyl-[acyl-carrier-protein] synthase 1 |
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| Ligand | BDBM50401027 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_881659 (CHEMBL2209290) |
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| IC50 | 3800±n/a nM |
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| Citation |  García, A; Bocanegra-García, V; Palma-Nicolás, JP; Rivera, G Recent advances in antitubercular natural products. Eur J Med Chem49:1-23 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 3-oxoacyl-[acyl-carrier-protein] synthase 1 |
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| Name: | 3-oxoacyl-[acyl-carrier-protein] synthase 1 |
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| Synonyms: | β-ketoacyl-ACP synthase I (KasA) | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | Beta-ketoacyl-ACP synthase (KasA) | KASA_MYCTU | kasA |
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| Type: | Protein |
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| Mol. Mass.: | 43305.57 |
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| Organism: | Mycobacterium tuberculosis |
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| Description: | P9WQD9 |
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| Residue: | 416 |
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| Sequence: | MSQPSTANGGFPSVVVTAVTATTSISPDIESTWKGLLAGESGIHALEDEFVTKWDLAVKI
GGHLKDPVDSHMGRLDMRRMSYVQRMGKLLGGQLWESAGSPEVDPDRFAVVVGTGLGGAE
RIVESYDLMNAGGPRKVSPLAVQMIMPNGAAAVIGLQLGARAGVMTPVSACSSGSEAIAH
AWRQIVMGDADVAVCGGVEGPIEALPIAAFSMMRAMSTRNDEPERASRPFDKDRDGFVFG
EAGALMLIETEEHAKARGAKPLARLLGAGITSDAFHMVAPAADGVRAGRAMTRSLELAGL
SPADIDHVNAHGTATPIGDAAEANAIRVAGCDQAAVYAPKSALGHSIGAVGALESVLTVL
TLRDGVIPPTLNYETPDPEIDLDVVAGEPRYGDYRYAVNNSFGFGGHNVALAFGRY
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| BDBM50401027 |
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| n/a |
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| Name | BDBM50401027 |
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| Synonyms: | CHEMBL2204380 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H30O3 |
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| Mol. Mass. | 294.429 |
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| SMILES | CCCCCCCc1cc(O)c(CCCCCC)c(=O)o1 |
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| Structure | 
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