| Reaction Details |
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 | Report a problem with these data |
| Target | Urokinase plasminogen activator surface receptor |
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| Ligand | BDBM50401188 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_881708 (CHEMBL2209754) |
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| IC50 | 11000±n/a nM |
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| Citation |  Wang, F; Eric Knabe, W; Li, L; Jo, I; Mani, T; Roehm, H; Oh, K; Li, J; Khanna, M; Meroueh, SO Design, synthesis, biochemical studies, cellular characterization, and structure-based computational studies of small molecules targeting the urokinase receptor. Bioorg Med Chem20:4760-73 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Urokinase plasminogen activator surface receptor |
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| Name: | Urokinase plasminogen activator surface receptor |
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| Synonyms: | CD_antigen=CD87 | MO3 | Monocyte activation antigen Mo3 | PLAUR | U-PAR | UPAR | UPAR_HUMAN | Urokinase plasminogen activator surface receptor | Urokinase receptor (uPAR) | Urokinase-type plasminogen activator/surface receptor |
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| Type: | Receptor |
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| Mol. Mass.: | 36979.14 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q03405 |
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| Residue: | 335 |
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| Sequence: | MGHPPLLPLLLLLHTCVPASWGLRCMQCKTNGDCRVEECALGQDLCRTTIVRLWEEGEEL
ELVEKSCTHSEKTNRTLSYRTGLKITSLTEVVCGLDLCNQGNSGRAVTYSRSRYLECISC
GSSDMSCERGRHQSLQCRSPEEQCLDVVTHWIQEGEEGRPKDDRHLRGCGYLPGCPGSNG
FHNNDTFHFLKCCNTTKCNEGPILELENLPQNGRQCYSCKGNSTHGCSSEETFLIDCRGP
MNQCLVATGTHEPKNQSYMVRGCATASMCQHAHLGDAFSMNHIDVSCCTKSGCNHPDLDV
QYRSGAAPQPGPAHLSLTITLLMTARLWGGTLLWT
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| BDBM50401188 |
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| n/a |
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| Name | BDBM50401188 |
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| Synonyms: | CHEMBL2205796 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H24N2O4 |
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| Mol. Mass. | 452.5012 |
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| SMILES | CC1CCCN(C1)c1cc(=Cc2ccc(cc2)C(O)=O)c2c(O)c3ccccc3c3onc1c23 |w:10.11| |
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| Structure | 
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