| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50401379 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_884050 (CHEMBL2215099) |
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| Ki | 4289±n/a nM |
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| Citation |  Banister, SD; Manoli, M; Doddareddy, MR; Hibbs, DE; Kassiou, M As(1) receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDs). Bioorg Med Chem Lett22:6053-8 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25266.54 |
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| Organism: | RAT |
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| Description: | Q9R0C9 |
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| Residue: | 223 |
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| Sequence: | MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRY
WAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
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| BDBM50401379 |
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| n/a |
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| Name | BDBM50401379 |
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| Synonyms: | CHEMBL2205830 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H25NO4 |
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| Mol. Mass. | 355.4275 |
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| SMILES | COc1cc(CN2C3C4C5C6C4C2(O)C2C6CC5C32)cc(OC)c1OC |TLB:7:18:9.10:16,12:14:9.10:16,THB:8:9:18.14:16,17:18:8.11:6,9:8:18.14:6,11:10:18.14:16,15:14:8.11:6,10:11:18.14:6,5:6:8.11:18.14| |
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| Structure | 
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