Reaction Details |
| Report a problem with these data |
Target | Delta-type opioid receptor |
---|
Ligand | BDBM50402018 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEMBL_886707 (CHEMBL2209607) |
---|
Ki | 47.5±n/a nM |
---|
Citation | Fujii, H; Imaide, S; Hirayama, S; Nemoto, T; Gouda, H; Hirono, S; Nagase, H Essential structure of opioid¿ receptor agonist nalfurafine for binding to the¿ receptor 3: synthesis of decahydro(iminoethano)phenanthrene derivatives with an oxygen functionality at the 3-position and their pharmacologies. Bioorg Med Chem Lett22:7711-4 (2012) [PubMed] Article |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Delta-type opioid receptor |
---|
Name: | Delta-type opioid receptor |
Synonyms: | DOR-1 | K56 | MSL-2 | OPIATE Delta | OPRD_MOUSE | Opioid receptors; mu and delta | Oprd1 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 40577.25 |
Organism: | MOUSE |
Description: | P32300 |
Residue: | 372 |
Sequence: | MELVPSARAELQSSPLVNLSDAFPSAFPSAGANASGSPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTQPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRTPCGRQEPGSLRRPRQATTRERVTAC
TPSDGPGGGAAA
|
|
|
BDBM50402018 |
---|
n/a |
---|
Name | BDBM50402018 |
Synonyms: | CHEMBL2204731 |
Type | Small organic molecule |
Emp. Form. | C28H38N2O4 |
Mol. Mass. | 466.6123 |
SMILES | CN([C@@H]1CC[C@@]2(O)[C@H]3CC4=C(C[C@H](O)CC4)[C@@]2(CCN3CC2CC2)C1)C(=O)\C=C\c1ccoc1 |r,t:9| |
Structure |
|