| Reaction Details |
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 | Report a problem with these data |
| Target | Carnitine O-palmitoyltransferase 1, liver isoform |
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| Ligand | BDBM50403028 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_887374 (CHEMBL2216983) |
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| IC50 | 240±n/a nM |
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| Citation |  Ceccarelli, SM; Chomienne, O; Gubler, M; Arduini, A Carnitine palmitoyltransferase (CPT) modulators: a medicinal chemistry perspective on 35 years of research. J Med Chem54:3109-52 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carnitine O-palmitoyltransferase 1, liver isoform |
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| Name: | Carnitine O-palmitoyltransferase 1, liver isoform |
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| Synonyms: | CPT I | CPT1 | CPT1-L | CPT1A | CPT1A_HUMAN | CPTI-L | Carnitine O-palmitoyltransferase I, liver isoform |
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| Type: | PROTEIN |
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| Mol. Mass.: | 88389.31 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_887463 |
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| Residue: | 773 |
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| Sequence: | MAEAHQAVAFQFTVTPDGIDLRLSHEALRQIYLSGLHSWKKKFIRFKNGIITGVYPASPS
SWLIVVVGVMTTMYAKIDPSLGIIAKINRTLETANCMSSQTKNVVSGVLFGTGLWVALIV
TMRYSLKVLLSYHGWMFTEHGKMSRATKIWMGMVKIFSGRKPMLYSFQTSLPRLPVPAVK
DTVNRYLQSVRPLMKEEDFKRMTALAQDFAVGLGPRLQWYLKLKSWWATNYVSDWWEEYI
YLRGRGPLMVNSNYYAMDLLYILPTHIQAARAGNAIHAILLYRRKLDREEIKPIRLLGST
IPLCSAQWERMFNTSRIPGEETDTIQHMRDSKHIVVYHRGRYFKVWLYHDGRLLKPREME
QQMQRILDNTSEPQPGEARLAALTAGDRVPWARCRQAYFGRGKNKQSLDAVEKAAFFVTL
DETEEGYRSEDPDTSMDSYAKSLLHGRCYDRWFDKSFTFVVFKNGKMGLNAEHSWADAPI
VAHLWEYVMSIDSLQLGYAEDGHCKGDINPNIPYPTRLQWDIPGECQEVIETSLNTANLL
ANDVDFHSFPFVAFGKGIIKKCRTSPDAFVQLALQLAHYKDMGKFCLTYEASMTRLFREG
RTETVRSCTTESCDFVRAMVDPAQTVEQRLKLFKLASEKHQHMYRLAMTGSGIDRHLFCL
YVVSKYLAVESPFLKEVLSEPWRLSTSQTPQQQVELFDLENNPEYVSSGGGFGPVADDGY
GVSYILVGENLINFHISSKFSCPETDSHRFGRHLKEAMTDIITLFGLSSNSKK
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| BDBM50403028 |
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| n/a |
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| Name | BDBM50403028 |
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| Synonyms: | CHEMBL2216769 |
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| Type | Small organic molecule |
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| Emp. Form. | C35H58N7O20P3S |
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| Mol. Mass. | 1021.856 |
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| SMILES | CCCCCCCC[C@H]1OC(=O)C(CSCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2OP(O)(O)=O)n2cnc3c(N)cnnc23)[C@@H]1C(O)=O |r| |
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| Structure | 
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