| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carnitine O-palmitoyltransferase 1, liver isoform |
|---|
| Ligand | BDBM50403031 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_887463 (CHEMBL2217072) |
|---|
| IC50 | 2400±n/a nM |
|---|
| Citation |  Ceccarelli, SM; Chomienne, O; Gubler, M; Arduini, A Carnitine palmitoyltransferase (CPT) modulators: a medicinal chemistry perspective on 35 years of research. J Med Chem54:3109-52 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carnitine O-palmitoyltransferase 1, liver isoform |
|---|
| Name: | Carnitine O-palmitoyltransferase 1, liver isoform |
|---|
| Synonyms: | CPT I | CPT1 | CPT1-L | CPT1A | CPT1A_HUMAN | CPTI-L | Carnitine O-palmitoyltransferase I, liver isoform |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 88389.31 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_887463 |
|---|
| Residue: | 773 |
|---|
| Sequence: | MAEAHQAVAFQFTVTPDGIDLRLSHEALRQIYLSGLHSWKKKFIRFKNGIITGVYPASPS
SWLIVVVGVMTTMYAKIDPSLGIIAKINRTLETANCMSSQTKNVVSGVLFGTGLWVALIV
TMRYSLKVLLSYHGWMFTEHGKMSRATKIWMGMVKIFSGRKPMLYSFQTSLPRLPVPAVK
DTVNRYLQSVRPLMKEEDFKRMTALAQDFAVGLGPRLQWYLKLKSWWATNYVSDWWEEYI
YLRGRGPLMVNSNYYAMDLLYILPTHIQAARAGNAIHAILLYRRKLDREEIKPIRLLGST
IPLCSAQWERMFNTSRIPGEETDTIQHMRDSKHIVVYHRGRYFKVWLYHDGRLLKPREME
QQMQRILDNTSEPQPGEARLAALTAGDRVPWARCRQAYFGRGKNKQSLDAVEKAAFFVTL
DETEEGYRSEDPDTSMDSYAKSLLHGRCYDRWFDKSFTFVVFKNGKMGLNAEHSWADAPI
VAHLWEYVMSIDSLQLGYAEDGHCKGDINPNIPYPTRLQWDIPGECQEVIETSLNTANLL
ANDVDFHSFPFVAFGKGIIKKCRTSPDAFVQLALQLAHYKDMGKFCLTYEASMTRLFREG
RTETVRSCTTESCDFVRAMVDPAQTVEQRLKLFKLASEKHQHMYRLAMTGSGIDRHLFCL
YVVSKYLAVESPFLKEVLSEPWRLSTSQTPQQQVELFDLENNPEYVSSGGGFGPVADDGY
GVSYILVGENLINFHISSKFSCPETDSHRFGRHLKEAMTDIITLFGLSSNSKK
|
|
|
|---|
| BDBM50403031 |
|---|
| n/a |
|---|
| Name | BDBM50403031 |
|---|
| Synonyms: | CHEMBL2216771 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H14O5S |
|---|
| Mol. Mass. | 342.366 |
|---|
| SMILES | OC(=O)C(=O)c1ccc(OCCOc2ccc3ccccc3c2)s1 |
|---|
| Structure | 
|
|---|
Search and Browse
